Increased serum concentrations of interleukin-6 (IL-6) and soluble IL-6 receptor in patients with Graves' disease.

@article{Salvi1996IncreasedSC,
  title={Increased serum concentrations of interleukin-6 (IL-6) and soluble IL-6 receptor in patients with Graves' disease.},
  author={Mario Salvi and Giuseppe Girasole and Mario Pedrazzoni and M. Passeri and Nicola. Giuliani and Roberta Minelli and Lewis E. Braverman and Elio Roti},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1996},
  volume={81 8},
  pages={2976-9}
}
Increased serum interleukin-6 (IL-6) concentrations have been reported in patients with thyroid destructive processes. In the present study we measured IL-6 and soluble IL-6 receptor (sIL-6R) concentrations in the serum of normal subjects and patients with Graves' disease using a high sensitivity sandwich enzyme-linked immunoassay. We found increased serum IL-6 and sIL-6R concentrations (69.3 fmol/L, and 964 pmol/L, respectively) in 49 hyperthyroid patients with Graves' disease (GD) compared to… CONTINUE READING

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