Increased secretion of pro-inflammatory cytokines by circulating polymorphonuclear neutrophils and regulation by interleukin 10 during intestinal inflammation.

Abstract

BACKGROUND Concentrations of pro-inflammatory cytokines are increased in the intestinal mucosa of patients with active inflammatory bowel disease (IBD). Polymorphonuclear neutrophil granulocytes (PMN) are the most abundant cell type in intestinal lesions in IBD. Interleukin 10 (IL-10) is an important contra-inflammatory cytokine which induces downregulation… (More)

Topics

Cite this paper

@article{Nikolaus1998IncreasedSO, title={Increased secretion of pro-inflammatory cytokines by circulating polymorphonuclear neutrophils and regulation by interleukin 10 during intestinal inflammation.}, author={Susanna Nikolaus and Juergen Bauditz and Paolo Gionchetti and Claudia M. Witt and Herbert D L{\"u}dtke Rainer D Ludvik Bernhard A Luger Lochs and S. Schreiber}, journal={Gut}, year={1998}, volume={42 4}, pages={470-6} }