Increased salivary gland tissue expression of Fas, Fas ligand, cytotoxic T lymphocyte-associated antigen 4, and programmed cell death 1 in primary Sjögren's syndrome.

@article{Bolstad2003IncreasedSG,
  title={Increased salivary gland tissue expression of Fas, Fas ligand, cytotoxic T lymphocyte-associated antigen 4, and programmed cell death 1 in primary Sj{\"o}gren's syndrome.},
  author={Anne Isine Bolstad and Hans Geir Eiken and Benedikte Rosenlund and Marta E. Alarc{\'o}n-Riquelme and Roland Jonsson},
  journal={Arthritis and rheumatism},
  year={2003},
  volume={48 1},
  pages={174-85}
}
OBJECTIVE To assess salivary gland tissues obtained from patients with primary Sjögren's syndrome (SS) for the gene expression profile of the candidate genes TNFRSF6 (Fas), TNFSF6 (FasL), SSA1 (Ro52 alpha and the splice variant Ro52 beta), SSB (La), CTLA4, PDCD1 (PD-1), and ORM2, which were selected on the basis of their putative participation in salivary gland inflammation. METHODS Quantitative real-time reverse transcriptase-polymerase chain reaction (RT-PCR) was used to examine the… CONTINUE READING
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