Increased risk of suicide under intrathecal ziconotide treatment? – A warning

@article{Maier2011IncreasedRO,
  title={Increased risk of suicide under intrathecal ziconotide treatment? – A warning},
  author={Christoph Maier and H Gockel and Kai Gruhn and Elena K. Krumova and Marc-Andreas Edel},
  journal={PAIN{\textregistered}},
  year={2011},
  volume={152},
  pages={235-237}
}
Despite some other known psychiatric adverse effects, ziconotide is recommended for intrathecal pain treatment with a good efficacy and safety. Although some hints in previous studies are apparent, a higher suicidality has not been accepted as a treatment risk of ziconotide treatment by the investigators in the former randomized controlled trials so far. We present two cases supporting the suspicion of ziconotide-induced suicidality. Both showed no depressive symptoms at the time of treatment… Expand
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