Increased risk of noninfluenza respiratory virus infections associated with receipt of inactivated influenza vaccine.

@article{Cowling2012IncreasedRO,
  title={Increased risk of noninfluenza respiratory virus infections associated with receipt of inactivated influenza vaccine.},
  author={Benjamin John Cowling and Vicky J Fang and Hiroshi Nishiura and Kwok-Hung Chan and Sophia Jinq Tyan Ng and Dennis Kai Ming Ip and Susan Shui Seng Chiu and Gabriel M. Leung and Joseph Sriyal Malik Peiris},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2012},
  volume={54 12},
  pages={
          1778-83
        }
}
We randomized 115 children to trivalent inactivated influenza vaccine (TIV) or placebo. Over the following 9 months, TIV recipients had an increased risk of virologically-confirmed non-influenza infections (relative risk: 4.40; 95% confidence interval: 1.31-14.8). Being protected against influenza, TIV recipients may lack temporary non-specific immunity that protected against other respiratory viruses. 
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