Increased risk of late posttraumatic seizures associated with inheritance of APOE epsilon4 allele.


BACKGROUND Late posttraumatic seizures are a common complication of moderate and severe traumatic brain injury. Inheritance of the apolipoprotein E (APOE) epsilon4 allele is associated with increased risk of Alzheimer disease, progression to disability in multiple sclerosis, and poor outcome after traumatic brain injury. OBJECTIVE To determine whether… (More)