Increased risk of large-bowel cancer in Crohn's disease with colonic involvement.

  title={Increased risk of large-bowel cancer in Crohn's disease with colonic involvement.},
  author={Anders Ekbom and Charles G Chad Helmick and Matthew M. Zack and H. O. Adami},
  volume={336 8711},
A cohort of 1655 patients with Crohn's disease diagnosed during 1983 in the Uppsala health care region, Sweden, was followed up with respect to the occurrence of colorectal cancer to the end of 1984. 12 colorectal cancers were diagnosed, yielding an increased overall risk of 2.5. The relative risk was similar for males and females. Duration of follow-up did not affect risk. Relative risk for disease of the terminal ileum only was 1.0; for terminal ileum and parts of colon 3.2; and for colon… CONTINUE READING
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