Increased risk of breast cancer following irradiation for Hodgkin's disease is not a result of ATM germline mutations.

@article{Broeks2000IncreasedRO,
  title={Increased risk of breast cancer following irradiation for Hodgkin's disease is not a result of ATM germline mutations.},
  author={Annegien Broeks and Nicola S. Russell and Arno N. Floore and Jos Urbanus and Ellen C Dahler and Mars van t Veer and Anton Hagenbeek and E. M. Noordijk and Mariad A. Crommelin and Flora E van Leeuwen and L J van T Veer},
  journal={International journal of radiation biology},
  year={2000},
  volume={76 5},
  pages={693-8}
}
PURPOSE Long-term survivors of Hodgkin's disease who received mantle-field irradiation at a young age have a strongly increased risk of developing breast cancer. The purpose of this study was to investigate whether this increased risk was substantially greater among women heterozygous for a germline mutation in the ataxia-telangiectasia gene (ATM). MATERIALS AND METHODS Thirty-two patients were selected who had developed breast cancer at least 10 years following irradiation for Hodgkin's… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…