Increased responses to lymphokines are correlated with preleukemia in mice inoculated with Moloney leukemia virus.


In various mouse strains, inoculation with Moloney leukemia virus results in the establishment of an acute viremia which in most cases is followed by the induction of leukemia. Also associated with the viremia is the development of a chronic cellular immune response detectable in vitro by the ability of viral proteins to induce splenic lymphocyte… (More)

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