Increased renal atrial natriuretic peptide synthesis in rats with deoxycorticosterone acetate-salt treatment.

@article{Lee1996IncreasedRA,
  title={Increased renal atrial natriuretic peptide synthesis in rats with deoxycorticosterone acetate-salt treatment.},
  author={Yong Jun Lee and Seog Jun Shin and Ma. Carmen S. Tan and Thomas J.C. Hsieh and Ju- He Tsai},
  journal={The American journal of physiology},
  year={1996},
  volume={271 4 Pt 2},
  pages={
          F779-89
        }
}
To investigate the role of renal synthesis of atrial natriuretic peptide (ANP) as a contributor to the water-sodium homeostasis, we studied the effects of electrolyte-water imbalance on renal ANP mRNA levels, plasma ANP concentrations, and urinary ANP excretion rates by using reverse transcription-polymerase chain reaction (PCR) and radioimmunoassay. Male Wistar rates divided into the following three groups: 1) the control group, 2) deoxycorticosterone acetate (DOCA)-salt-treated group, and 3… CONTINUE READING
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