Increased release of matrix metalloproteinase-9 in the plasma of acute severe asthmatic patients.


BACKGROUND Matrix metalloproteinases (MMPs) are likely to be relevant mediators of the extracellular matrix (ECM) degradation and airway remodelling. OBJECTIVE We have compared the levels of MMPs, eotaxin and soluble interleukin 2 receptor (IL-2R) in the plasma of healthy subjects, atopic patients and asthmatic patients. METHODS The asthmatic patients… (More)