Increased rectal mucosal expression of interleukin 1beta in recently acquired post-infectious irritable bowel syndrome.

@article{Gwee2003IncreasedRM,
  title={Increased rectal mucosal expression of interleukin 1beta in recently acquired post-infectious irritable bowel syndrome.},
  author={Kok-Ann Gwee and Stephen M. Collins and Nicholas W. Read and Andrea Rajnakova and Yongjian Deng and J Christopher Graham and Michael W McKendrick and Shabbir M. Moochhala},
  journal={Gut},
  year={2003},
  volume={52 4},
  pages={523-6}
}
BACKGROUND AND AIMS Chronic bowel disturbances resembling irritable bowel syndrome (IBS) develop in approximately 25% of patients after an episode of infectious diarrhoea. Although we have previously shown that psychosocial factors operating at the time of, or prior to, the acute illness appear to predict the development of post-infectious IBS (PI-IBS), our finding of an increased inflammatory cell number in the rectum persisting for at least three months after the acute infection suggested… CONTINUE READING
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