Increased proportions of dendritic cells and recovery of IFNγ responses in HIV/HCV co-infected patients receiving ART.

@article{Saraswati2016IncreasedPO,
  title={Increased proportions of dendritic cells and recovery of IFNγ responses in HIV/HCV co-infected patients receiving ART.},
  author={Henny Saraswati and Silvia Lee and Dino B A Tan and Evy Yunihastuti and Rino Alvani Gani and Patricia Price},
  journal={Human immunology},
  year={2016},
  volume={77 1},
  pages={29-34}
}
Dendritic cell (DC) numbers and functions can be affected by HIV and HCV disease, but the effects of antiretroviral therapy (ART) on DC and the implications of these changes are unclear. We examined circulating DC in samples from Indonesian patients beginning ART with advanced HIV disease and documented mild/moderate HCV hepatitis. Frequencies of myeloid and plasmacytoid DC increased after 6 months on ART, but frequencies of DC producing IL-12 or IFNα following stimulation with TLR agonists… CONTINUE READING
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