Increased production of vascular endothelial growth factor in the lesions of atopic dermatitis

@article{Zhang2006IncreasedPO,
  title={Increased production of vascular endothelial growth factor in the lesions of atopic dermatitis},
  author={Yan Zhang and Hiroaki Matsuo and Eishin Morita},
  journal={Archives of Dermatological Research},
  year={2006},
  volume={297},
  pages={425-429}
}
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by severe itching, erythema and edema resistant to anti-histamine therapy. Vascular endothelial growth factor (VEGF) is a potent agent that causes hyperpermeability of blood vessels and endothelial cell proliferation, and might be involved in the persisting erythema and edema in AD. In this study, we used extraction of stratum corneum with physiological saline to detect VEGF produced in the lesions of AD. Biological… CONTINUE READING

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