Increased production of IL-1alpha and TNF-alpha in lipopolysaccharide-stimulated blood from obese patients with non-alcoholic fatty liver disease.

@article{Poniachik2006IncreasedPO,
  title={Increased production of IL-1alpha and TNF-alpha in lipopolysaccharide-stimulated blood from obese patients with non-alcoholic fatty liver disease.},
  author={Jaime Poniachik and Attila Csendes and Juan Carlos Diaz and Jorge Alberto Chavez Rojas and Patricio Alfonso Burdiles and Fernando Maluenda and Gladys Smok and Ram{\'o}n Rodrigo and Luis A Videla},
  journal={Cytokine},
  year={2006},
  volume={33 5},
  pages={252-7}
}
Enhanced pro-inflammatory cytokine production is considered a pathogenic factor in non-alcoholic fatty liver disease (NAFLD). Peripheral blood production of interleukin-1alpha (IL-1alpha) and tumor necrosis factor-alpha (TNF-alpha) was studied in relation to the severity of histological changes of the liver in obese NAFLD patients. Basal levels in serum and production of IL-1alpha and TNF-alpha in peripheral blood cell cultures after stimulation with lipopolysaccharide (enzyme-linked… CONTINUE READING
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Direct stimulation of cytokines (IL-1b, TNF-a, IL-6, IL-2, IFM-g and GM-CSF) in whole blood. I. Comparison with isolated PBMC stimulation

  • D De Groote, PF Zangerle, Y Gevaert, MF Fassote, Y Beguin, F Noizat- Pirenne
  • Cytokine
  • 1992
Highly Influential
13 Excerpts

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