Increased prevalence of semaphorin 3C, a repellent of sympathetic nerve fibers, in the synovial tissue of patients with rheumatoid arthritis.

@article{Miller2004IncreasedPO,
  title={Increased prevalence of semaphorin 3C, a repellent of sympathetic nerve fibers, in the synovial tissue of patients with rheumatoid arthritis.},
  author={Luitpold E Miller and Claudia Weidler and Werner Falk and Peter Angele and Jens Schaumburger and Juergen Schoelmerich and Rainer H Straub},
  journal={Arthritis and rheumatism},
  year={2004},
  volume={50 4},
  pages={1156-63}
}
OBJECTIVE The presence of selective sympathetic nerve repellents, i.e., semaphorins, may be responsible for the observed reduction of sympathetic innervation in the synovial tissue of patients with rheumatoid arthritis (RA). This study was undertaken to investigate the presence of different semaphorins in synovial tissue of patients with RA, patients with osteoarthritis (OA), and control subjects without inflammation. METHODS In situ hybridizations with digoxigenin-labeled RNA probes directed… CONTINUE READING
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