Increased prefrontal cortex interleukin-2 protein levels and shift in the peripheral T cell population in progressive supranuclear palsy patients

@inproceedings{Rydbirk2019IncreasedPC,
  title={Increased prefrontal cortex interleukin-2 protein levels and shift in the peripheral T cell population in progressive supranuclear palsy patients},
  author={Rasmus Rydbirk and Betina Elfving and Jonas Folke and Bente Pakkenberg and Kristian Winge and Tomasz Brudek and Susana Aznar},
  booktitle={Scientific Reports},
  year={2019}
}
Accumulating evidence suggests neuroinflammation to be an integrated feature of neurodegeneration. Profiling inflammatory mediators across diseases may reveal common and disease-specific signatures. Here, we focused on progressive supranuclear palsy (PSP), a tauopathy presenting motor and cognitive dysfunction. We screened for 21 cytokines and growth factors in the dorsomedial prefrontal cortex of 16 PSP and 16 control brains using different quantitative techniques. We found and validated… CONTINUE READING
BETA

Similar Papers

References

Publications referenced by this paper.
SHOWING 1-10 OF 42 REFERENCES

A Language and Environment for Statistical Computing v

  • 3.4.1
  • 2017

The movement disorder society criteria

Höglinger, G. U. et al. Clinical diagnosis of progressive supran palsy
  • Mov Disord 32, 853–864, https://doi.org/10.1002/mds.26987
  • 2017

wide spectrum of structural MRI finding in cases of pathologically proven progressive supranuclear palsy

Sakurai, K. et al. Beyond the midbrain atrophy
  • Neuroradiology 59, 431–443, https://doi.org/10.1007/s00234-017-1812-4
  • 2017
VIEW 3 EXCERPTS

Alzheimer, Parkinson, Creutzfeldt-Jakob and Tauopathies

I. López González, P. Garcia-Esparcia, +3 authors Transcriptomic Profiles of Inflammation in Neurodegenerative Diseases
  • Int J Mol Sci 17, 206, https://doi. org/10.3390/ijms17020206
  • 2016