Increased platelet concentration does not improve functional graft healing in bio-enhanced ACL reconstruction

@article{Fleming2014IncreasedPC,
  title={Increased platelet concentration does not improve functional graft healing in bio-enhanced ACL reconstruction},
  author={Braden C. Fleming and Benedikt L. Proffen and Patrick Vavken and Matthew R. Shalvoy and Jason Timothy Machan and Martha Meaney Murray},
  journal={Knee Surgery, Sports Traumatology, Arthroscopy},
  year={2014},
  volume={23},
  pages={1161-1170}
}
The use of an extracellular matrix scaffold (ECM) combined with platelets to enhance healing of an anterior cruciate ligament (ACL) graft (“bio-enhanced ACL reconstruction”) has shown promise in animal models. However, the effects of platelet concentration on graft healing remain unknown. The objectives of this study were to determine whether increasing the platelet concentration in the ECM scaffold would (1) improve the graft biomechanical properties and (2) decrease cartilage damage after… CONTINUE READING