Increased platelet, leukocyte and endothelial microparticles predict enhanced coagulation and vascular inflammation in pulmonary hypertension

@article{Diehl2010IncreasedPL,
  title={Increased platelet, leukocyte and endothelial microparticles predict enhanced coagulation and vascular inflammation in pulmonary hypertension},
  author={Philipp Diehl and Miriam Aleker and Thomas Helbing and Verena Sossong and Martin Germann and Stephan Sorichter and Christoph Bode and Martin Moser},
  journal={Journal of Thrombosis and Thrombolysis},
  year={2010},
  volume={31},
  pages={173-179}
}
Pulmonary hypertension (PH) is associated with platelet activation, vascular inflammation and endothelial dysfunction leading to often life threatening thrombo-embolic complications. Microparticles (MPs) are cell vesicles with strong coagulatory and inflammatory effects being released during cell activation and apoptosis. As there are currently no established surrogate markers predicting platelet activation and pro-coagulation in PH patients, the aim of the study was to analyze different pro… CONTINUE READING

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