Increased plasma markers of inflammation and endothelial dysfunction and their association with microvascular complications in Type 1 diabetic patients without clinically manifest macroangiopathy.

@article{Targher2005IncreasedPM,
  title={Increased plasma markers of inflammation and endothelial dysfunction and their association with microvascular complications in Type 1 diabetic patients without clinically manifest macroangiopathy.},
  author={Giovanni Targher and Lorenzo Bertolini and Giacomo Zoppini and Luciano Zenari and Giancarlo Falezza},
  journal={Diabetic medicine : a journal of the British Diabetic Association},
  year={2005},
  volume={22 8},
  pages={999-1004}
}
AIMS To evaluate whether plasma biomarkers of inflammation and endothelial dysfunction differed in Type 1 diabetic patients as compared with those in non-diabetic subjects, and to examine the association of these biomarkers with early stages of microvascular complications. METHODS Plasma biomarkers of inflammation [fibrinogen, hs-C-reactive protein (hs-CRP)] and endothelial dysfunction [von Willebrand factor (v-WF), intercellular adhesion molecule-1, plasminogen activator inhibitor-1 (PAI-1… CONTINUE READING