Increased plasma levels of 8-iso-PGF2alpha and IL-6 in an elderly population with depression.

@article{Dimopoulos2008IncreasedPL,
  title={Increased plasma levels of 8-iso-PGF2alpha and IL-6 in an elderly population with depression.},
  author={Nikolaos P. Dimopoulos and Christina Piperi and Vassiliki Psarra and Robert William Lea and Anastasios Th. Kalofoutis},
  journal={Psychiatry research},
  year={2008},
  volume={161 1},
  pages={59-66}
}
Oxidative damage and immune-inflammatory activation have been suggested to play a role in depression. The purpose of the study was to investigate possible associations and interactions of these pathophysiological mechanisms in geriatric depression by determining the levels of plasma 8-iso-prostaglandin F(2alpha) (8-iso-PGF(2alpha)) and interleukin-6 (IL-6) in elderly depressed individuals. Subjects over 60 years of age with depression and controls were randomly selected from a population in the… CONTINUE READING

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