Increased plasma interleukin-8 concentrations in alcoholic hepatitis.

  title={Increased plasma interleukin-8 concentrations in alcoholic hepatitis.},
  author={Daniell B. Hill and Luis S. Marsano and C J Mcclain},
  volume={18 3},
Patients with alcoholic hepatitis often have hepatic polymorphonuclear leukocyte infiltration and neutrophilia. Interleukin-8 is a cytokine that stimulates neutrophil chemotaxis and release of lysosomal enzymes. It is made by several types of cells, including fibroblasts, Kupffer cells and hepatocytes. In this study, serial plasma interleukin-8 concentrations were measured with enzyme-linked immunosorbent assay in 40 consecutive patients with moderate-to-severe alcoholic hepatitis over a 6-mo… CONTINUE READING
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