Increased plasma bile alcohol glucuronides in patients with cerebrotendinous xanthomatosis: effect of chenodeoxycholic acid.

@article{Batta1987IncreasedPB,
  title={Increased plasma bile alcohol glucuronides in patients with cerebrotendinous xanthomatosis: effect of chenodeoxycholic acid.},
  author={Ashok Kumir Batta and Gerald Salen and Sarah Shefer and G. Stephen Tint and Moushira Batta},
  journal={Journal of lipid research},
  year={1987},
  volume={28 8},
  pages={1006-12}
}
Large quantities of C27 bile alcohols hydroxylated at C-25 are excreted in the bile and urine of patients with cerebrotendinous xanthomatosis, a lipid storage disease that results from defective bile acid synthesis. The presence of both biliary and urinary bile alcohols reflects impaired bile acid synthesis. After treatment of samples with beta-glucuronidase, plasma bile alcohols were quantitated by gas-liquid chromatography-mass spectrometry. 5 beta-Cholestane-3 alpha,7 alpha,12 alpha,25… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-5 of 5 references

Di- agnosis of cerebrotendinous xanthomatosis (CTX) and effect of chenodeoxycholic acid therapy by analysis of urine using capillary gas chromatography

  • B. G. Wolthers, M. Volmer, J. van der Molen, B. J. Koopman, A.E.J. de Jager, R. J. Wattereus
  • Clin. Chim. Acta
  • 1983
Highly Influential
5 Excerpts

The structure and function of the blood - brain barrier

  • P. S. Roheim
  • Federation Proc .
  • 1984

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