Increased plasma MMP-2 protein expression in lymph node-positive patients with colorectal cancer

@article{Langenskild2004IncreasedPM,
  title={Increased plasma MMP-2 protein expression in lymph node-positive patients with colorectal cancer},
  author={Marcus Langenski{\"o}ld and Lena Holmdahl and Peter Falk and M Ivarsson},
  journal={International Journal of Colorectal Disease},
  year={2004},
  volume={20},
  pages={245-252}
}
Degradation of the extracellular matrix plays an important part during the invasion of cancer cells into the surrounding tissue. The matrix metalloproteinases (MMPs) have a central role in this process as demonstrated in different malignancies. The aim of this study was to investigate the presence of several MMPs from tumour, adjacent tumour-free colon segment and from plasma, in order to evaluate how these factors might be used as predictors in colorectal malignancy. Seventy-two patients who… CONTINUE READING

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