Increased peripheral benzodiazepine binding sites in the brain of patients with Huntington's disease.

@article{Messmer1998IncreasedPB,
  title={Increased peripheral benzodiazepine binding sites in the brain of patients with Huntington's disease.},
  author={Kirsten Messmer and Gavin Paul Reynolds},
  journal={Neuroscience letters},
  year={1998},
  volume={241 1},
  pages={53-6}
}
Huntington's disease (HD) is a hereditary disorder associated with the development of dyskinesias and dementia, characterised by profound atrophy of the striatum and, to a lesser extent, other brain areas. A relative gliosis has been described. One marker for such inflammatory gliosis is an elevation of peripheral type benzodiazepine binding sites (PTBBS); these have also been shown to be increased following acute experimental and chronic degenerative neuronal damage. The present study… CONTINUE READING

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