Increased oxacillin activity associated with glycopeptides in coagulase-negative staphylococci

@article{Domaracki1998IncreasedOA,
  title={Increased oxacillin activity associated with glycopeptides in coagulase-negative staphylococci},
  author={B. E. Domaracki and Ann Evans and Karen E Preston and Henry S. Fraimow and R. Venezia},
  journal={European Journal of Clinical Microbiology and Infectious Diseases},
  year={1998},
  volume={17},
  pages={143-150}
}
Vancomycin resistance in methicillin-resistant staphylococci presents a potential therapeutic problem. In order to understand the impact of low-level vancomycin resistance in coagulase-negative Staphylococci, stepwise selection of vancomycin resistance was accomplished by growingstaphylococcus haemolyticus in culture media with increasing concentrations of vancomycin. A >40-fold increase in susceptibility to β-lactam antibiotics was observed. No obvious alterations in the growth curve, the… CONTINUE READING

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