Increased osteoclast activity in the presence of increased homocysteine concentrations.

@article{Herrmann2005IncreasedOA,
  title={Increased osteoclast activity in the presence of increased homocysteine concentrations.},
  author={Markus Herrmann and Thomas Widmann and Graziana Colaianni and Silvia Concetta Colucci and Alberta Zambonin Zallone and Wolfgang Herrmann},
  journal={Clinical chemistry},
  year={2005},
  volume={51 12},
  pages={2348-53}
}
BACKGROUND Increased plasma homocysteine (HCY) may be an independent risk factor for osteoporotic fractures and therefore may also adversely affect bone metabolism. We analyzed the effect of HCY on human osteoclast (OC) activity. METHODS We cultured peripheral blood mononuclear cells from 17 healthy male donors [median (SD) age, 30 (5) years] for 20 days… CONTINUE READING