Increased olfactory bulb volume and olfactory function in early blind subjects

@article{Rombaux2010IncreasedOB,
  title={Increased olfactory bulb volume and olfactory function in early blind subjects},
  author={Philippe Rombaux and Caroline Huart and Anne G De Volder and Isabel Cuevas and Laurent Renier and Thierry Duprez and C{\'e}cile B. Grandin},
  journal={NeuroReport},
  year={2010},
  volume={21},
  pages={1069–1073}
}
It has been shown that the volume of the olfactory bulb (OB) changes with function. The aim of this study was to investigate whether the OB volume and the olfactory function in early blind (EB) subjects increase compared with controls. Psychophysical testing of olfactory performances and OB volumetric measurements assessed by an MRI scan were studied. Quantitative olfactory function expressed in the odor discrimination and odor-free identification scores was higher in EB subjects compared with… 
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References

SHOWING 1-10 OF 27 REFERENCES
Correlation of olfactory function with changes in the volume of the human olfactory bulb.
TLDR
The human OB is a highly plastic structure that responds to individual changes in olfactory status and is demonstrated in a longitudinal study for the first time to the authors' knowledge.
Olfactory bulb volume in the clinical assessment of olfactory dysfunction.
TLDR
The actual knowledge regarding olfactory bulb function, practical ways to measure ofactory bulb volume and olfatory sulcus depth, and systematic observations regarding these measurements related to various causes of Olfactory dysfunction, e.g. infection of the upper respiratory tract, head trauma, or neurodegenerative disease are discussed.
Increasing olfactory bulb volume due to treatment of chronic rhinosinusitis--a longitudinal study.
TLDR
Results of this study support the idea that stimulation of olfactory receptor neurons impacts on the cell death in the Olfactory bulb, not only in rodents but also in humans.
Olfactory Bulb Volume in Taiwanese Patients with Posttraumatic Anosmia
TLDR
OB volumes were significantly lower in Taiwanese patients with posttraumatic anosmia, and the influence of different disorders on OB volume was investigated.
Reduced olfactory bulb volume in post-traumatic and post-infectious olfactory dysfunction
TLDR
Findings indicate that smell deficits leading to a reduced sensory input to the olfactory bulb result in structural changes at the level of the bulb.
Olfactory Bulb and Tract and Temporal Lobe Volumes: Normative Data across Decades a
TLDR
The sense of smell shows a diminution with age as measured by the University of Pennsylvania Smell Identification Test (UPSIT), and normative data by decades can be used to assess the OBTs of cohorts of patients with neurodegenerative disorders that affect olfaction.
[Sense of smell in deaf and blind patients].
TLDR
The present results showed that attention focusing on olfactory tasks by lowering of auditory or visual inputs did not enhance the Olfactory performances of the control subjects and the visually-impaired subjects did not perform better then the controlSubjects.
Smell and taste function in the visually impaired
TLDR
The data imply that blindness, per se, has little influence on chemosensory function and add further support to the notion that specialized training enhances performance on a number of chemosENSory tasks.
Odour discrimination and identification are improved in early blindness
Improved auditory spatial tuning in blind humans
TLDR
Comparisons of behavioural and electrophysiological indices of spatial tuning within central and peripheral auditory space in congenitally blind and normally sighted but blindfolded adults test the hypothesis that the effects of visual deprivation might be more pronounced for processing peripheral sounds.
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