Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors.

@article{Sanacora2002IncreasedOC,
  title={Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors.},
  author={Gerard S Sanacora and Graeme F. Mason and Douglas L. Rothman and John H. Krystal},
  journal={The American journal of psychiatry},
  year={2002},
  volume={159 4},
  pages={663-5}
}
OBJECTIVE Studies have demonstrated low concentrations of gamma-aminobutyric acid (GABA) in the plasma and CSF of individuals with major depression, and low GABA concentrations have also been found in the occipital cortex of depressed subjects. The goal of this study was to determine whether these occipital cortex GABA concentrations are altered after administration of selective serotonin reuptake inhibitors (SSRIs) in the treatment of depression. METHOD By means of proton magnetic resonance… CONTINUE READING
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