Increased nitric oxide levels in patients with rheumatoid arthritis.

  title={Increased nitric oxide levels in patients with rheumatoid arthritis.},
  author={Yukitaka Ueki and Satoshi Miyake and Yoshihiro Tominaga and Katsumi Eguchi},
  journal={The Journal of rheumatology},
  volume={23 2},
OBJECTIVES We determined whether serum levels of nitric oxide (NO) correlate with disease activity of rheumatoid arthritis (RA) and inflammatory cytokines by measuring the serum and synovial fluid (SF) concentrations of NO in patients with RA and patients with osteoarthritis (OA) and healthy subjects. METHODS The concentration of NO in each sample was determined by chemiluminescence. Cytokine levels were determined using sandwich enzyme-linked immunoassays. RESULTS The mean serum… CONTINUE READING


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