Increased nitric oxide in nasal lavage fluid and nitrotyrosine formation in nasal mucosa--indices for severe perennial nasal allergy.

Abstract

BACKGROUND The nose contributes the large amount of nitric oxide (NO) to exhaled air. NO is a mediator of vasodilation and yields peroxynitrite (ONOO-) by reacting with superoxide (O2-). ONOO attacks tyrosine residues to form nitrotyrosine. OBJECTIVE The aim of this study was to examine the pathophysiological role of NO in nasal mucosa in patients with… (More)

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Cite this paper

@article{Sato1998IncreasedNO, title={Increased nitric oxide in nasal lavage fluid and nitrotyrosine formation in nasal mucosa--indices for severe perennial nasal allergy.}, author={M. Sato and Norio Fukuyama and M. Sakai and Hiroshi Nakazawa}, journal={Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology}, year={1998}, volume={28 5}, pages={597-605} }