Increased nerve fiber expression of sensory sodium channels Nav1.7, Nav1.8, And Nav1.9 in rhinitis.

@article{Keh2008IncreasedNF,
  title={Increased nerve fiber expression of sensory sodium channels Nav1.7, Nav1.8, And Nav1.9 in rhinitis.},
  author={Siew M Keh and Paul Facer and Karen D Simpson and Gurpreet S Sandhu and Hesham A Saleh and P. R. Vijai Anand},
  journal={The Laryngoscope},
  year={2008},
  volume={118 4},
  pages={573-9}
}
INTRODUCTION Voltage-gated sodium channels Nav1.7, Nav1.8, and Nav1.9 are involved in nerve action potentials and have been proposed to underlie neuronal hypersensitivity. We have therefore studied their levels in allergic and nonallergic rhinitis. MATERIALS AND METHODS Inferior turbinate biopsies from 50 patients (n = 18 controls, n = 20 allergic, and n = 12 nonallergic rhinitis) were studied by immunohistology using antibodies to Nav1.7, Nav1.8, and Nav1.9, the structural nerve marker… CONTINUE READING