Increased need for thyroxine in women with hypothyroidism during estrogen therapy.

  title={Increased need for thyroxine in women with hypothyroidism during estrogen therapy.},
  author={Baha M. Arafah},
  journal={The New England journal of medicine},
  volume={344 23},
BACKGROUND Women with hypothyroidism that is being treated with thyroxine often need higher doses when they are pregnant. Whether this need can be attributed solely to estrogen-induced increases in serum thyroxine-binding globulin or whether other factors are involved is not known. METHODS In 11 postmenopausal women with normal thyroid function and 25 postmenopausal women with hypothyroidism treated with thyroxine, I assessed thyroid function before they started estrogen therapy and every 6… CONTINUE READING
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