Increased myocardial collagen turnover in patients with progressive cardiac conduction disease.

@article{Bozkaya2008IncreasedMC,
  title={Increased myocardial collagen turnover in patients with progressive cardiac conduction disease.},
  author={Yasemin Turan Bozkaya and Hikmet Hakan Aydin and Handan A K Celik and Meral Kayikçioğlu and Serdar Payzin and Hakan Kultursay and Mehmet Kasim Aydin and Murat Yeşil and Levent Hurkan Can and Can Hasdemir},
  journal={Pacing and clinical electrophysiology : PACE},
  year={2008},
  volume={31 10},
  pages={1284-90}
}
BACKGROUND Histopathologically, progressive cardiac conduction disease (PCCD) is characterized by progressive fibrosis and sclerodegenerative changes in the proximal and distal conduction system of the heart. Therefore, we sought to determine the serum levels of myocardial collagen turnover markers, extracellular matrix components, transforming growth factor beta(1) (TGFbeta(1)), and bone morphogenic protein-7 (BMP-7) in this population. METHODS Study population included 20 patients (6 M/14 F… CONTINUE READING