Increased mitochondrial creatine kinase in chronically stimulated fast-twitch rabbit muscle.

@article{Schmitt1985IncreasedMC,
  title={Increased mitochondrial creatine kinase in chronically stimulated fast-twitch rabbit muscle.},
  author={Thierry Gilles Schmitt and Drik Pette},
  journal={FEBS letters},
  year={1985},
  volume={188 2},
  pages={
          341-4
        }
}
Fractional extraction and isozyme electrophoresis revealed the presence of small amounts (2.5% of total cellular activity) of mitochondrial creatine kinase (CK) in rabbit fast-twitch muscle. Chronic nerve stimulation resulted in a decrease of extramitochondrial MM-CK to 60% of its normal value but induced an approx. 4-fold increase in mitochondrial CK. This increase occurred in parallel with the rise in enzyme activities of terminal substrate oxidation. 
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