Increased miR-708 expression in NSCLC and its association with poor survival in lung adenocarcinoma from never smokers.

@article{Jang2012IncreasedME,
  title={Increased miR-708 expression in NSCLC and its association with poor survival in lung adenocarcinoma from never smokers.},
  author={Jin Sung Jang and H Jeon and Zhifu Sun and Marie Christine Aubry and Hui Tang and Cheol-Hong Park and Fariborz Rakhshan and Debra A. Schultz and Christopher P. Kolbert and Ruth Lupu and Jae Yong Park and Curtis C. Harris and Ping Yang and Jin Jen},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2012},
  volume={18 13},
  pages={
          3658-67
        }
}
PURPOSE miRNA plays an important role in human disease and cancer. We seek to investigate the expression status, clinical relevance, and functional role of miRNA in non-small cell lung cancer. EXPERIMENTAL DESIGN We conducted miRNA expression profiling in matched lung adenocarcinoma and uninvolved lung using 56 pairs of fresh-frozen (FF) and 47 pairs of formalin-fixed, paraffin-embedded (FFPE) samples from never smokers. The most differentially expressed miRNA genes were evaluated by Cox… CONTINUE READING
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