Increased methylglyoxal and oxidative stress in hypertensive rat vascular smooth muscle cells.

@article{Wu2002IncreasedMA,
  title={Increased methylglyoxal and oxidative stress in hypertensive rat vascular smooth muscle cells.},
  author={Ling-Yun Wu and Bernhard H. J. Juurlink},
  journal={Hypertension},
  year={2002},
  volume={39 3},
  pages={
          809-14
        }
}
Methylglyoxal can yield advanced glycation end products via nonenzymatic glycation of proteins. Whether methylglyoxal contributes to the pathogenesis of hypertension has not been clear. The aim of the present study was to investigate whether the levels of methylglyoxal and methylglyoxal-induced advanced glycation end products were enhanced and whether methylglyoxal increased oxidative stress, activated nuclear factor-kappaB (NF-kappaB), and increased intracellular adhesion molecule-1 (ICAM-1… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 94 CITATIONS

FILTER CITATIONS BY YEAR

2003
2018

CITATION STATISTICS

  • 9 Highly Influenced Citations

  • Averaged 6 Citations per year over the last 3 years

References

Publications referenced by this paper.
SHOWING 1-10 OF 31 REFERENCES

Oxidative stress induces NF- B nuclear translocation without degradation of I B

  • TG Canty, Jr., +4 authors TH. Pohlman
  • Hypertension
  • 2002

Similar Papers

Loading similar papers…