Increased lysine content in rice grains by over-accumulation of BiP in the endosperm.

@article{Kawakatsu2010IncreasedLC,
  title={Increased lysine content in rice grains by over-accumulation of BiP in the endosperm.},
  author={Taiji Kawakatsu and Shuyi Wang and Yuhya Wakasa and F. Takaiwa},
  journal={Bioscience, biotechnology, and biochemistry},
  year={2010},
  volume={74 12},
  pages={2529-31}
}
Over-accumulation of lysine-rich binding protein (BiP) in the rice endosperm caused strong endoplasmic reticulum (ER) stress and reduced seed storage proteins, resulting in a relative increase in nutritionally balanced non-seed storage proteins. We show that transgenic rice with over-accumulated BiP was a high-lysine rice germplasm and that the over-accumulation of BiP in the endosperm offered a unique strategy to improve the lysine content of cereal grains. 
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