Increased local recurrence and reduced survival from colorectal cancer following anastomotic leak: systematic review and meta-analysis.

@article{Mirnezami2011IncreasedLR,
  title={Increased local recurrence and reduced survival from colorectal cancer following anastomotic leak: systematic review and meta-analysis.},
  author={Alexander H. Mirnezami and Reza Mirnezami and Kandiah Chandrakumaran and Kishore K. Sasapu and Peter Sagar and Paul J. Finan},
  journal={Annals of surgery},
  year={2011},
  volume={253 5},
  pages={890-9}
}
OBJECTIVE To examine the long-term oncological impact of anastomotic leakage (AL) after restorative surgery for colorectal cancer using meta-analytical methods. Outcomes evaluated were local recurrence, distant recurrence, and survival. BACKGROUND Recurrence after potentially curative surgery for colorectal cancer remains a significant clinical problem and has a poor prognosis. AL may be a risk factor for disease recurrence, however available studies have been conflicting. A meta-analysis was… CONTINUE READING
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