Increased lipolysis and its consequences on gluconeogenesis in non-insulin-dependent diabetes mellitus.

@article{Nurjhan1992IncreasedLA,
  title={Increased lipolysis and its consequences on gluconeogenesis in non-insulin-dependent diabetes mellitus.},
  author={N. Nurjhan and Agostino Consoli and John E. Gerich},
  journal={The Journal of clinical investigation},
  year={1992},
  volume={89 1},
  pages={169-75}
}
The present studies were undertaken to determine whether lipolysis was increased in non-insulin-dependent diabetes mellitus (NIDDM) and, if so, to assess the influence of increased glycerol availability on its conversion to glucose and its contribution to the increased gluconeogenesis found in this condition. For this purpose, we infused nine subjects with NIDDM and 16 age-, weight-matched nondiabetic volunteers with [2-3H] glucose and [U-14C] glycerol and measured their rates of glucose and… CONTINUE READING

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