Increased levels of transition metals in breast cancer tissue.

  title={Increased levels of transition metals in breast cancer tissue.},
  author={John G Ionescu and Jan Novotny and Vera D. M. Stejskal and Anette L{\"a}tsch and Eleonore Blaurock-Busch and Marita Eisenmann-Klein},
  journal={Neuro endocrinology letters},
  volume={27 Suppl 1},
OBJECTIVES High levels of transition metals such as iron, nickel, chromium, copper, and lead are closely related to free radical generation, lipid peroxidation, formation of DNA strand breaks, and tumor growth in cellular systems. In order to determine the correlation to malignant growth in humans, we investigated the accumulation of heavy metals in 20 breast cancer biopsies and compared the findings to the levels found in 8 healthy biopsies. METHODS The concentration of transition metals in… CONTINUE READING
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