Increased levels of serum and tissue miR-107 in human gastric cancer: Correlation with tumor hypoxia.

@article{Ayremlou2015IncreasedLO,
  title={Increased levels of serum and tissue miR-107 in human gastric cancer: Correlation with tumor hypoxia.},
  author={Nooshin Ayremlou and Hossein Mozdarani and Seyed Javad Mowla and Alireza Delavari},
  journal={Cancer biomarkers : section A of Disease markers},
  year={2015},
  volume={15 6},
  pages={851-60}
}
BACKGROUND MicroRNAs can function as oncogenes and tumor suppressor genes in human cancers. The expression of miR-107 is high in various types of solid tumors. OBJECTIVE The aim of this study was to evaluate the tumor and serum level of miR-107 and its correlation to HIF-1α expression in gastric cancer patients. METHODS Quantitative real-time PCR was used to analyze the expression of miR-107 and HIF-1α in 36 pairs of fresh gastric cancer and matched adjacent normal tissue specimens and the… CONTINUE READING
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