Increased levels of glutathione in bronchoalveolar lavage fluid from patients with asthma.

@article{Smith1993IncreasedLO,
  title={Increased levels of glutathione in bronchoalveolar lavage fluid from patients with asthma.},
  author={Lewis Smith and Michael Houston and Jeff Anderson},
  journal={The American review of respiratory disease},
  year={1993},
  volume={147 6 Pt 1},
  pages={1461-4}
}
Patients with asthma generate increased amounts of reactive oxygen species (ROS) from peripheral blood cells and cells recovered by bronchoalveolar lavage (BAL). ROS produce many of the pathophysiologic changes associated with asthma and may contribute to its pathogenesis. Although antioxidant defenses inhibit the changes produced by ROS, no data are available on local antioxidant defenses in asthma. The present study was designed to begin to explore these defenses by measuring superoxide… CONTINUE READING