Increased levels of a particular phosphatidylcholine species in senescent human dermal fibroblasts in vitro

@article{Naru2011IncreasedLO,
  title={Increased levels of a particular phosphatidylcholine species in senescent human dermal fibroblasts in vitro},
  author={E. Naru and Y. Takanezawa and Misako Kobayashi and Y. Misaki and K. Kaji and K. Arakane},
  journal={Human Cell},
  year={2011},
  volume={21},
  pages={70-78}
}
Plasma membranes are essential components of living cells, and phospholipids are major components of cellular membranes. Here, we used liquid chromatography/mass spectrometry to investigate changes in the membrane phospholipid content that occur in association with aging. Our results indicate that the levels of a particular species of phosphatidylcholine comprised of stearic acid and arachidonic acid increased with age. To determine the reason forthe increased levels of this particular… Expand
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19 Caveolar Vesicles in Cellular Senescence

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