Increased level of IL-32 during human immunodeficiency virus infection suppresses HIV replication.

@article{Rasool2008IncreasedLO,
  title={Increased level of IL-32 during human immunodeficiency virus infection suppresses HIV replication.},
  author={Sahibzada Tasleem Rasool and Heng Tang and Jianmei Wu and Wei Li and Muhammad Mahmood Mukhtar and Jingwen Zhang and Yongxin Mu and Huang Xioa Xing and Jianguo Wu and Ying Zhu},
  journal={Immunology letters},
  year={2008},
  volume={117 2},
  pages={161-7}
}
Interleukin-32 was recently identified as a pro-inflammatory cytokine produced by T-lymphocytes, natural killer cells, epithelial cells, and blood monocytes. IL-32 is induced by IFN-gamma in a time-dependent manner suggesting a role for IL-32 in innate and adaptive immune responses. In this study we present evidence that Human immunodeficiency virus promotes interleukin-32 production at both mRNA and protein levels. Our results showed that there is a 74% increase in the serum levels of IL-32… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 20 references

IL-32, a proinflammatory cytokine in rheumatoid arthritis.

Proceedings of the National Academy of Sciences of the United States of America • 2006

Proteinase 3 is an IL-32 binding protein.

Proceedings of the National Academy of Sciences of the United States of America • 2006

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