Increased leukotriene B4 and interleukin-6 in exhaled breath condensate in cystic fibrosis.

@article{Carpagnano2003IncreasedLB,
  title={Increased leukotriene B4 and interleukin-6 in exhaled breath condensate in cystic fibrosis.},
  author={Giovanna Elisiana Carpagnano and Peter J Barnes and Duncan M. Geddes and Margaret E. Hodson and Sergei A. Kharitonov},
  journal={American journal of respiratory and critical care medicine},
  year={2003},
  volume={167 8},
  pages={1109-12}
}
Chronic neutrophilic airway inflammation is an important feature of cystic fibrosis (CF). Noninvasive inflammatory markers may be useful in monitoring CF. Leukotriene B4 (LTB4) and interleukin (IL)-6 are inflammatory mediators that are increased in chronic neutrophilic inflammation. The aim of this study was to assess whether LTB4 and IL-6 were increased in exhaled breath condensate of CF patients and whether they could be used to monitor inflammation. Twenty patients with CF (13 males, age of… CONTINUE READING

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