Increased invasion activity of endometrial stromal cells and elevated expression of matrix metalloproteinase messenger RNA in the uterine tissues of mice with experimentally induced adenomyosis.

@article{Matsuda2001IncreasedIA,
  title={Increased invasion activity of endometrial stromal cells and elevated expression of matrix metalloproteinase messenger RNA in the uterine tissues of mice with experimentally induced adenomyosis.},
  author={Masako Matsuda and Hiroyuki Sasabe and Yashusi Adachi and Toshikazu Suzuki and Taisuke Mori},
  journal={American journal of obstetrics and gynecology},
  year={2001},
  volume={185 6},
  pages={1374-80}
}
OBJECTIVE This study was undertaken to determine whether changes in stromal cell invasiveness and matrix metalloproteinase activity in mouse uterine tissues were involved in the development of adenomyosis that was induced by ectopic pituitary grafting. STUDY DESIGN The invasion activity of endometrial stromal cells into various kinds of extracellular matrix components was examined in experimentally induced adenomyotic and control uteri in vitro. The effect of an inhibitor of matrix… CONTINUE READING