Increased intramuscular lipid storage in the insulin-resistant and endurance-trained state

@article{Loon2005IncreasedIL,
  title={Increased intramuscular lipid storage in the insulin-resistant and endurance-trained state},
  author={L. J. Loon and B. Goodpaster},
  journal={Pfl{\"u}gers Archiv},
  year={2005},
  volume={451},
  pages={606-616}
}
  • L. J. Loon, B. Goodpaster
  • Published 2005
  • Medicine, Chemistry
  • Pflügers Archiv
  • Numerous studies have reported a strong correlation between intramuscular triacylglycerol (IMTG) content and insulin resistance. However, the proposed relationship between IMTG accumulation and skeletal muscle insulin resistance is not unambiguous, as trained athletes have been shown to be markedly insulin sensitive despite an elevated IMTG storage. Though the latter has often been attributed to differences in muscle fibre type composition and/or structural characteristics of the… CONTINUE READING
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    References

    SHOWING 1-10 OF 112 REFERENCES
    Intramyocellular lipid content in type 2 diabetes patients compared with overweight sedentary men and highly trained endurance athletes.
    • 210
    • Highly Influential
    • PDF
    Lipotoxicity: the obese and endurance-trained paradox
    • A. Russell
    • Medicine
    • International Journal of Obesity
    • 2004
    • 63
    • Highly Influential
    • PDF
    Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes.
    • 956
    • PDF
    Intramuscular triglyceride and muscle insulin sensitivity: evidence for a relationship in nondiabetic subjects.
    • 409
    Ceramide content is increased in skeletal muscle from obese insulin-resistant humans.
    • 585
    • PDF
    Exercise training increases intramyocellular lipid and oxidative capacity in older adults.
    • 160
    • PDF
    Fuel selection in human skeletal muscle in insulin resistance: a reexamination.
    • 867
    • PDF
    The increase in intramyocellular lipid content is a very early response to training.
    • 131
    • PDF
    Influence of prolonged endurance cycling and recovery diet on intramuscular triglyceride content in trained males.
    • 60
    • PDF