Increased interleukin-10 and interferon-γ levels in Plasmodium vivax malaria suggest a reciprocal regulation which is not altered by IL-10 gene promoter polymorphism

@article{Medina2011IncreasedIA,
  title={Increased interleukin-10 and interferon-γ levels in Plasmodium vivax malaria suggest a reciprocal regulation which is not altered by IL-10 gene promoter polymorphism},
  author={Tiago S. Medina and Sheyla P. T. Costa and Maria D.L. Oliveira and A. M. Ventura and Jos{\'e} M Souza and T. F. Gomes and A. C. Vallinoto and M. P{\'o}voa and J. Silva and M. G. Cunha},
  journal={Malaria Journal},
  year={2011},
  volume={10},
  pages={264 - 264}
}
  • Tiago S. Medina, Sheyla P. T. Costa, +7 authors M. G. Cunha
  • Published 2011
  • Medicine, Biology
  • Malaria Journal
  • BackgroundIn human malaria, the naturally-acquired immune response can result in either the elimination of the parasite or a persistent response mediated by cytokines that leads to immunopathology. The cytokines are responsible for all the symptoms, pathological alterations and the outcome of the infection depends on the reciprocal regulation of the pro and anti-inflammatory cytokines. IL-10 and IFN-gamma are able to mediate this process and their production can be affected by single nucleotide… CONTINUE READING
    On the cytokine/chemokine network during Plasmodium vivax malaria: new insights to understand the disease
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