Increased inositol 1,4,5-trisphosphate accumulation correlates with an up-regulation of bradykinin receptors in Alzheimer's disease.

@article{Huang1995IncreasedI1,
  title={Increased inositol 1,4,5-trisphosphate accumulation correlates with an up-regulation of bradykinin receptors in Alzheimer's disease.},
  author={Hui Ming Huang and T A Lin and Grace Y Sun and Gary E Gibson},
  journal={Journal of neurochemistry},
  year={1995},
  volume={64 2},
  pages={
          761-6
        }
}
  • Hui Ming Huang, T A Lin, +1 author Gary E Gibson
  • Published in Journal of neurochemistry 1995
  • Biology, Medicine
  • An alteration in signal transduction systems in Alzheimer's disease (AD) would likely be of pathophysiological significance, because these processes control normal brain functions. Previously, a diminished beta-adrenergic-mediated cyclic AMP response was found in cultured fibroblasts from AD patients. Because cross-talk between the phosphoinositide and cyclic AMP pathways exists, the phosphoinositide cascade was studied under conditions that were similar to those for studying the cyclic AMP… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    Citations

    Publications citing this paper.
    SHOWING 1-7 OF 7 CITATIONS

    Peripheral markers in testing pathophysiological hypotheses and diagnosing Alzheimer's disease.

    VIEW 3 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    Ionic and signal transduction alterations in Alzheimer’s disease

    VIEW 1 EXCERPT
    CITES BACKGROUND

    Neuroprotective Signal Transduction